He Qing's absence made Wan Qing's burden even heavier, but she didn't say anything, but silently took over the work that originally belonged to He Qing, and shouldered the burden alone.
In the process of cooperation among the three parties, the dawn of the first stage is finally about to usher in. It is well known that in the replication of RNA viruses, the helicase encoded by the virus, as well as the RNA molecular chaperone, play an extremely important role in unraveling the RNA double strands generated during the replication process and remodeling the viral RNA.
At present, in the world, rna viruses have basically been confirmed to encode their own helicase or rna molecular chaperone. But at the same time, whether norovirus encodes a helicase or an rna molecular chaperone has been an unresolved problem.
In the laboratory collaboration of Huai Ru and Wan Qing, it was discovered for the first time that the norovirus ns3 protein has both the function of ATP-dependent RNA helicase and the function of ATP-independent RNA chaperone.
The unwinding function of ns3 means that it can promote the rna replication of norovirus, which plays a crucial role in the activity of norovirus.
In addition, Zhang Xingzhi's research also found that the ns3 unwinding activity of norovirus can actually be inhibited by small molecule drugs that have been approved for marketing. Experiments have shown that this drug can effectively inhibit the RNA replication of norovirus at the cellular level.
It can be said that the cooperation of the three-party laboratories ushered in the first phase of important results. It is also because the research on norovirus encoding a viral protein with rna helicase and molecular chaperone activity was discovered for the first time, so it has aroused the attention of many people in the industry in advance through gossip.
Many researchers in the same industry have sent emails to the laboratories of Huairu and Wanqing, trying to find the latest progress of some experiments. After all, the role and mechanism of norovirus in RNA replication actually provided a new idea for their research and development work on norovirus.
On this day, Huairu was looking at the materials in the office, and Wan Qing was beside him, with her hands on the table, and the two of them were discussing the progress of the experiment these days with great interest. The discussion was a bit too involved, and both of them were very satisfied with the summary results on the materials.
As he was talking, Huai Ru raised his head and bumped into Wan Qing's forehead. Wan Qing fell down on the chair unexpectedly, and the two couldn't help laughing as they looked at each other.
After all, people are in high spirits on happy occasions, and even with the incense sticks on Huairu's table, Wan Qing feels that the fragrance permeates just right. She leaned closer and smelled it, and then asked with a smile: "You must have changed the brand, right? Why is the smell different from the previous one?"
Huai Ru's voice sounded mellow: "The fragrance is still the same, but if the person who smells it has a heart and turns around in the internal organs, the taste seems to be different."
After listening, Wan Qing "giggled" and laughed, the voice was crisp and clear. The moment his mouth was grinning, since his face was full of joy, Huai Ru was also happy when he saw it.
"ßËßËßË" There was a knock on the door suddenly, Wan Qing quickly stopped laughing, and the two looked out the door together. At this time, there was an unexpected figure standing at the door, Huai Ru opened his mouth, unable to speak for a while in surprise.
The light from the door slowly poured in, and standing in the shadows was Bi Shijian with huge bags under his eyes. His mouth was smacked and pursed from time to time, and the lines on both sides of his nose were like barren fields reclaimed by iron plows.
"Hey, Teacher Bi, why are you here?" Huai Ru hurriedly got up and walked to the door to greet him.
Bi Shijian turned his head inappropriately, coughed twice, caught sight of Wan Qing out of the corner of his eye, and didn't know whether to go in and talk, or just stand at the door.
"You guys talk, I still have something to do, I'm going back to the research institute first." Wan Qing picked up the information bag, and simply gave up the office. (Remember the site URL: www.hlnovel.com