It is a long process from paper to physical object, from equipment to application, and then to paper. The high efficiency of the shotgun method, one piece at a time, and its lack of accuracy are always a contradiction. However, history has proven that the shotgun method is the ultimate winner, but it only needs to overcome some key points. The method currently used by the academic community and planned to be used by the Human Genome Project is the cloning method one by one. In English, it is also easy to remember. It is called clone by clone, one clone after another. The shotgun method or the shotgun method is to shoot out a piece of the body with one shot, and then pull the body back to assemble it. If we want to make a metaphor, the academic community currently uses rifles, one shot at a time, and the effect is very good if the shot is accurate. The shotgun method is more like a machine gun. It sweeps a large area. From time to time, fish will slip through the net, but it doesn't matter. The more you sweep, the coverage will still be satisfactory. In fact, in the face of dense enemies, machine guns are still easy to use. It¡¯s just that before that, the machine gun faced too many problems. How to continue to supply orders? How to solve the heating problem? How to solve logistical problems? How to solve the weight problem of the gun body? Yang Rui¡¯s paper today is a paper about solving a problem. In terms of style, the style of such an article is actually not very high. It is a tactical article at best. Not to mention being compared with strategic articles from a high position, it is comparable to tactical explanatory articles, such as "Implementation of the Human Genome Project" ¡·This kind of comparison is a bit weak. However, style is more like a chain of contempt, just a universal concept. To truly judge the value of an article, you still have to look at the problem it solves - the paper must solve the problem after all, strategic articles solve strategic problems, tactical articles, sometimes the problems solved show the breakthrough point in the future, such as the steam engine , such as internal combustion engines, such as electric motors, such as aircraft, missiles, satellites, such as machine guns, routers and PCRs. "By adopting computers on a large scale, we can solve the last bottleneck of the shotgun method, if we complete the puzzle problem. Of course, the speed and cost of today's computers are more problematic, but in this regard, I believe in the development of the computer industry itself , will give us a lot of help" Yang Rui simply read the paper aloud, without much emotion, and there was no need for emotional recitation. Using emotional resonance to attract the attention of scientists is not what scientists do. For Yang Rui, this is just another routine project research, but for scholars in the field, it is another earth-shaking change. Yang Rui¡¯s thinking is very logical, which is evaluated from the perspective of praise. To be honest, Yang Rui¡¯s thinking is actually very crude. He just had an idea: I think it¡¯s easiest to demolish the home in the middle. ?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????¡ Other scholars would let go of a tower that was difficult to dismantle, and would give in when an enemy attacked. Yang Rui didn¡¯t think about this at all and simply explained: Just do it! Of course, there are also some good rookies. The most powerful thing is that Yang Rui solved it all the way and finally got the answer. After reading a paper, the whole place was silent. The conclusion is really surprising. ?In other words, the conclusion after argumentation is too unexpected. While everyone is still mocking the stupidity of the shotgun method, Yang Rui has used irrefutable numbers to prove the superiority of the shotgun method in the Human Genome Project. So, is the paper by Nobel Prize winner Comrade Yang Rui true? Most people will not doubt Yang Rui now. Doubt is the most unreasonable thing. ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? being changed, but the change is too big to accept. If the paper is true, many biological laboratories will have to change their previously constructed genetic testing models. "Professor Yang, you should publish your paper earlier." "Actually, there is no need to save such an article. If you publish it earlier, you don't have to scare everyone into giving up their research." "Yes, I need to change my direction. , It¡¯s too uncomfortable.¡± Scholars were talking a lot, and those who stood up to ask questions were not so much doubters as those who did not accept reality. The crude solution to the problem is a bit better. The answer is practical and there are not so many twists and turns. If the human body is compared to a square, the Human Genome Project wants to know the location and identity of everyone in the square. How does the one-by-one cloning method work: It asks these people one by one. Where is Yang Rui¡¯s shotgun technique? He just hit them suddenly, shooting out a square of minced meat, and then sent his subordinates to smash the minced meat, and then get to know the faces of the people. ??What do you have to question about this way of solving problems? The corpses are all in their original positions. If you don¡¯t believe it, go check it out. Yang Rui answered one by one, as skillfully as an old butcher. In just a few words, he dismantled a pig until its shape was no longer visible. Scholars seek certification of familiar parts. Once confirmed, the butcher's work is completed. ??Everyone buys meat and goes home. Stew soup when it is necessary, braise when it is braised, sweet and sour when it is necessary, and the world is harmonious and unified. As for the lean pigs sold by the butcher next door, no one cares about them, no one else is to blame. Who told you to choose a bad pig? With Yang Rui joining in, the regular meeting of the Human Genome Project ended in silence. What Yang Rui brought back was not only specific work arrangements, but also praise and resentment from the academic community. Of course, for the Peking University Ion Channel Laboratory, Sinovel Laboratory, or Peking University itself, praise and resentment are both excellent things. In such an atmosphere, even the media became much more obedient and only reported some progress of the Human Genome Project as usual. Yang Rui rarely had peace for two days. When it was time to get back on the plane, several media came to interview us again. Maybe it¡¯s because we have a few days to buffer, so the media¡¯s questions are more targeted. In addition to the routine personal gossip and industry gossip, a reporter suddenly attacked and said: "Professor Yang, you said in your speech that using the shotgun method requires deploying a large number of computers. Will the same be true for your research in China? "Of course." Yang Ru nodded. The reporter secretly took out his knife and asked: "Can the Chinese government provide such a large amount of funds and equipment?" "Well, I am going to invest some money myself as start-up capital." Yang Rui said and explained: "The Nobel Prize bonus, Especially the profits from sildenafil, I am ready to invest in it. "In fact, it is naturally impossible to make so much, but at this time, there is no need to hold back. The reporter nodded, his face full of excitement. Everyone knows that the Nobel Prize prize money is huge, and the income from sildenafil is estimated to be even more indispensable. In an instant, several reporters had already made several article titles in their minds: "Chinese scientists raise funds for scientific research themselves" "The consequences of the Chinese government's cuts in scientific research funding are revealed" "China's Yang Sells Property" "Clone Sheep" "My father is in financial trouble" Yang Rui doesn't care. On the one hand, the total amount of funds he invested is actually not high. From the official launch of the Human Genome Project to the present, the investment is less than 5 million U.S. dollars. The 5 million U.S. dollars budgeted for the later period must be endless. On the other hand, the Human Genome Project is not really without benefits. It just depends on whether he wants to take advantage of it. If necessary, Yang Rui will not be a late addition. Of course, the most important thing is that Yang Rui is rich now. Not counting the later profits from sildenafil, the US dollar cash in his hands has exceeded 1 billion US dollars. In terms of net worth, drugs such as deferiprone are valued at US$1 billion, not to mention sildenafil. Companies like Sinovel are worth more. If Yang Rui takes a longer view, the hundreds of courtyard houses in the capital, as well as the collections in the courtyards, as well as dozens of unit buildings, as well as the Yao Valley and millions of houses in Shanghai and Shenzhen, all make Yang Rui interested. My understanding of money has greatly changed. ? ? ? ? ? ? ? ? ? ?Money can¡¯t buy me happiness, that¡¯s how it is. Yang Rui didn¡¯t even bother to argue with the ministries and commissions. ¡°But for the mass media, this story was too predictable. ???????????????????????????????????????? Is spending your own money on basic research a lunatic or just sensationalism? Is it a myth or is it true? Is it the regression of society or the inaction of the country When Yang Rui's plane landed and he went to school after a day's rest, the Peking University Triangle was already full of comments. Some students organized themselves spontaneously and approached Yang Rui, vowing: "Professor Yang, if everyone uses their own money to do research, China's scientific research will really be over. We will petition the school leaders on your behalf." " No, it's not necessary." Yang Rui answered guiltily. He wanted to say that the school leaders and I were of the same mind, but Peking University today did not have tens of millions of dollars in spare cash. The students only regarded Yang Rui as a thin-faced man, and all of them were indignant.He said nervously: "If you don't say it, let's go do it. It makes no sense that Nobel Prize winners can't do research because of money. Does such a big China still lack such a little money?" Before Yang Rui could open his mouth again, the first person said The students had already raised their hands and shouted slogans, then turned and ran towards the administration building. Yang Rui looked at the backs of the students, feeling a little funny and a little touched. It is naturally impossible to get the desired results if you report tens of millions of dollars to the school leaders. However, this is something they risked getting a bad allocation or even losing their diploma. "Call Professor Cai and say something." Yang Rui said to Xu Zhengping, then pulled the book and Geng Xin gave a few instructions. He didn't call himself to avoid being questioned. On the contrary, Yang Rui simply went into the laboratory and conducted experiments behind closed doors, thinking that if he did not come forward, the discussions outside would gradually die down.