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Chapter 105 New Pattern

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    Nowadays, ZSK's money-making pattern is different. It used to rely on IT, and later relied on finance to make steady money. When the opportunity came, it also used the financial crisis to earn capitalists' hard-earned money, and now it focuses on necessities.  The three most important things during Iceland¡¯s state of emergency: food, medicine and oil.  Petroleum is energy. Needless to say, energy is being developed. Food is driven by aquaBounty's efforts in genetically modified animals.  The most important investment is the drug design project. The Ladder Laboratory Cloud, which is being carried out globally, has a net investment of more than 10 billion per year. More than 10,000 scientists work for Ladder, which is exciting, but most of them are engaged in the research and development of breakthrough drugs, so  It is difficult to make any breakthroughs. He has always been out of the sight of the media and is only active in academia.

    In March of this year, the U.S. law just authorized the production of biosimilars. In June, the world's number one medical journal "The New England Journal of Medicine" published a blockbuster article. Because it was too academic, it did not generate much news among ordinary people.  response, but finally the media in Massachusetts began to explain the core content to the public: ZSK¡¯s new company [Ladder Pharmaceuticals] has made breakthroughs in the field of biosimilars and may be approved by the FDA. The biosimilars it produces are exempt from clinical trials.  .  This year's biosimilar market is only about US$200 million, but in the future the annual market compound growth rate will reach 56%, reaching a huge 20 billion within ten years.  It is reported that the Ladder Fund has been conducting research in the field of biosimilars for six years and has invested tens of billions of dollars, exceeding the investment of all other pharmaceutical companies in the world. It is a bit like the United States¡¯ investment in the military, which exceeds the investment of all other pharmaceutical companies in the world.  The sum of nations.

    The even more amazing news is that Ladder Pharmaceuticals has also made significant progress in the biopharmaceutical process. The purification process of biopharmaceuticals accounts for about 80% of the entire cost, and Ladder Pharmaceuticals¡¯ research results have made purification faster, purer, and cheaper.  It is possible to reduce costs by 90%. In this way, generic drugs may actually drive patented drugs out of the market and dominate one area. When the patented drugs expire, one brand will be destroyed.  ZSK's younger brother will add another important younger brother. No one will say that ZSK is an ignorant child in the biological field.  Forbes, who likes to calculate money for others, actually believes that the valuation of Ladder Pharmaceutical is no less than that of Kong Zero Electronics, because the global biopharmaceutical industry will reach nearly 100 billion by next year. As long as 50% of companies adopt the purification process of Ladder Pharmaceutical, then Ladder Pharmaceutical will  The pharmaceutical industry has a value of 50 billion in its hands. It is truly a prehistoric giant in the pharmaceutical industry.

    The generic drug market is divided into chemical generics and biosimilars. Once the patent of the former expires, its market price will drop by 90%. Because chemical pharmaceuticals have simple processes and simple ingredients, currently developing countries can basically only produce a few.  A chemical generic drug.  The cost of production and research and development of biosimilars is extremely high, and it is difficult for the produced products to be exactly the same as the patented products, so they have to undergo clinical trials that take several years. Even if they are produced, their selling price will only be  dropped by 10%.  Ladder Pharmaceutical has overcome two problems of complete replication and high-efficiency and high-quality purification in one fell swoop. This is because ZSK is not short of money and does not need financing, otherwise the capital market will definitely cry and give money to ZSK.

    For the biopharmaceutical giants, this is a big headache for their giants, but for Obama, it is a huge blessing. Holy shit, ZSK is really a match made in heaven for me. I am pursuing universal health insurance. The biggest opposition voice  I just think that medical expenses remain high. They are already too high now. Are you still going to give me universal medical insurance? Will I be able to survive?  At present, the average American pays more than 8,000 US dollars for health insurance every year. Once universal medical insurance is implemented, this number will reach 13,000 US dollars in the future, and the entire United States' health insurance expenditure will reach an astonishing 4.6 trillion US dollars.

    You tell the pharmaceutical giants, can you sell it cheaper?  If people don't abandon you, it's their lifeblood, so they just rely on this patent to make a living.  Well now, you have to be cheap even if you are not cheap, the wolf is coming!  The highly motivated White House has urged the FDA to accelerate the formulation of biosimilar policies and vigorously support the construction of ladder pharmaceutical factories.

    The stocks of pharmaceutical giants such as Pfizer, GlaxoSmithKline, and Sanofi plummeted.

    At the same time, Sikong Ling submitted his doctoral thesis on computer-aided drug design to Harvard University - D-Protein Life.

    The paper describes the D-protein single-cell life he designed. It is a very primitive life, similar to bacteria, and can replicate itself through RNA. However, this is an artificial life form completely designed by a computer. In order to convince his peers,  This organism is specifically constructed using D-protein.  D-protein is an artificial protein, which is different from natural protein. Life now existing in nature is composed of L-protein. This is also one of the evidences that all life originates from the same living organism. D and L types  Proteins have a mirror image relationship. It has long been known theoretically that nature can produce D-type life, but there is no complete D-type life in nature, and only a small amount of D-protein exists.  Sikong Ling's paper created this species, which is enough to shock the biological science community.

    This thesis was completed by Sikong Ling**. In addition to the guidance of his supervisor, it also required the efforts of thousands of scientists and cost hundreds of millions. It is definitely not something ordinary doctoral students can do.  This is also the first time I have solved the problem. There are a lot of awesome people all over the world.Biological scientists and biotechnology engineers went to study the thesis of a shabby doctoral student to see how it related to the achievements of Ladder Pharmaceuticals, which has become very popular recently.  Could this type of D-type organism really have something to do with 100% replication or efficient purification?  ZSK will not tell you so that you will never be able to tear yourself apart!

    Mr. Sikong finally received his doctorate. In his graduation photo, he stood in the center with a calm expression. He was surrounded by several of Harvard University's best biologists, including his mentor, and behind him were his classmates. All these characters were in full swing.  He is his employee, showing the domineering attitude of a generation of pseudo-academic masters.

    Duanmuzhen was most concerned about his career. After reading dozens of relevant popular science reports, he hurriedly sent him a private message: Come and set up a pharmaceutical factory here quickly!

    Sikong Ling¡¯s reply was: Don¡¯t worry, I¡¯m going to the imperial capital to talk to the elders about traditional Chinese medicine.

    It's a pity that the elders don't like the disobedient young man. The last time he suddenly opened the door before the Olympics, he broke the hearts of the elders. The elders held a special elders meeting for the young man. The standards were high and rare in the world, but  I don¡¯t understand the young man¡¯s complete stranglehold on the traditional Chinese medicine industry. Even if the young man can bring a compensatory industrial chain worth hundreds of billions to China¡¯s pharmaceutical industry, he will not be able to seduce the Presbyterian Council to reach an agreement.  There are millions of practitioners, what a big movement this is. Besides, there are still quite a few academicians of the Academy of Sciences and the Academy of Engineering who recognize the value of traditional Chinese medicine, which shows that this is at least "controversial" and is not just a teenager who got a Harvard Pharmacy degree.  You can hold on with a doctorate degree.

    ????????????????????????????????????????????????????????????????? Seeing that bunch of slutty academicians telling lies and deceiving the king, and surrounding the young man with a sense of powerlessness, this is really a magical country.  This is a question of trust and confidence, and if you can't gain trust, forget it.  The boy stayed in the suite of the Diaoyutai State Guesthouse where the head of state was received for ten days, and talked nonsense with the elders and academicians for ten days. He left the imperial capital sadly, even canceling the appointment with the old man of the Duanmu family, who had retired.  As a deputy state-level leader of the Department of Foreign Affairs, this breach of contract is not a trivial matter in the eyes of ordinary people.

    When Sikong Ling came to Dong Province, Moriki Sakamoto, CEO of the Association for the Promotion of Modern Medicine, submitted to him a proposal to open a guidance hospital in every provincial capital city in China and build a wide range of franchised community hospitals based on it.  All doctors in community hospitals are certified and supervised by the Medical Promotion Association, and all drugs and equipment are provided by the Medical Promotion Association for patients who trust the Medical Promotion Association.  This plan cost a huge 10 billion.  In fact, it¡¯s not much, just over one billion US dollars.  Sikong Ling said in a low mood: "Just do whatever you want."

    Sakamoto: "What's wrong with Sikong-kun? Have you lost confidence? Giving up is not Sikong-kun's style! This is a long and protracted battle. We first provide good health services to those who trust the Society for the Promotion of Modern Medicine. This is already good."  ¡±

    Sikong Ling: "I understand, as I said before, it's up to you."

    Sakamoto knew what he was going through in the Imperial Capital, so he patted him on the shoulder and quietly retreated. Anyway, as long as the BOSS agreed to pay him.

    Sikong Ling spent a few days with the expectant mother Murong in Magic Island City before lazily heading to Xijing City, Western Province to visit the governor there who was invited to visit.

    Duanmuzhen knew that he would definitely support him, so he even selected the site of the pharmaceutical factory and took him to see the place as soon as he arrived.

    When I got out of the No. 2 car in Xi Province, I saw, wow, it¡¯s such a big piece of land, and it¡¯s free of charge. It¡¯s really generous.

    Duanmu Yun happily introduced how she would instruct various ministries of the provincial government to cooperate to strive for greater speed, greater savings, and build a national biopharmaceutical industry center.

    Last year, the total GDP of Western Province was only 800 billion. The sudden introduction of an industrial chain worth 100 billion will definitely be a stimulant for the economic development of Western Province.

    Sikong Ling: ¡°Can the provincial government stop all budgets for traditional Chinese medicine education, cultivation, and production?¡±

    Duanmu Yu: "It will have a huge impact on farmers who grow traditional Chinese medicine and a lot of people in the industrial chain. I am afraid there will be too much resistance in the provincial party committee, but I will try to reduce it as much as possible and will not increase investment."

    Sikong Ling: "Well, I don't expect you to have such a strong prestige. In this way, the traditional Chinese medicine industry will be reduced by 100 million, and I will let Ladder Pharmaceutical create a value of 200 million. If you destroy traditional Chinese medicine, maybe tens of billions will be generated.  The new value comes, you can figure it out yourself."

    Duanmu Yun: "This you hate Chinese medicine to this extent."

    Sikong Ling said calmly: "How can there be any hatred? It's just a strategy, just like when religious elements preach, they must recruit two people to join the religion in their lifetime before they can go to heaven."

    He then added: "Let them stop playing tricks. Our Association for the Promotion of Modern Medicine has more complete data than your provincial government!"

    This is a good idea. Keep fighting. If the Western Province cannot do its job, we will invite bids from the whole country. Those who are willing to destroy Chinese medicine will come and be rewarded!

    Lord Sikong, this is too high.In fact, no one came to receive the reward within a month. The poor boy could only look up to the sky and laugh to express his loneliness.

    Western Province is a place with such backward concepts and extremely powerful traditional Chinese medicine. Of course, even if the governor promotes it, it will be useless. Instead, her prestige, which is not much, will be hit. Look, the female governor is beautiful, but her ability is average.  Like drops.

    In order to prevent Sikong Ling from continuing to increase his influence in the Celestial Dynasty, the Council of Elders issued a secret order, and all media units voluntarily reduced their reporting of news about Sikong Ling, and included this in the promotion assessment, and began to guard against thieves.

    ¡°Hey, modern medicine is so difficult anyway, forget it, let¡¯s build a pharmaceutical factory in the Western Province, so that her hard work will not be in vain.

    There is a huge development gap in the entire Western Province. Sikong Ling¡¯s hometown is particularly backward. However, the economic foundation of Xijing City is not bad, but there are more heavy industries and poor air quality. Moreover, humans developed this area relatively early, and most of it has been overused.  , there are people everywhere, and building a factory in such a place is a bit against Sikong Ling's wishes.

    Sikong Ling asked the governor: "Can you change the place? The scenery is better, otherwise I won't want to come here anymore."

    The final location was chosen in Xiling City, a famous tourist attraction, and it is only famous in Xi Province and has only been lightly developed. It is indeed the best place, and you can find a good place wherever you look.  Xiling City is far away from the industrial center. The air is good, but there is insufficient electricity. We are discussing with the Ministry of Energy to build a nuclear power plant there to keep Xiling City clean and beautiful forever.

    Planning and construction of a provincial science and technology park with considerable potential has begun.

    In August, another baby was born in the Sikong family after Tutu. He may not be the first baby to have "two mothers," but he is probably the first baby whose father deliberately tried to reconcile the two mothers.  Only when they thought the baby was their own did they understand how clever this political strategy was.  The two mothers strongly denied Sikong Saidong's weird name, so Sikong Ling gave his son a name that was even more domineering than Duanmu Ba - Sikong Jian!  Later, Xue's mother felt that she would be laughed at by the children: If you don't learn the eighteen martial arts, you are a fool to learn!  Then change it to Sikong Jian, the pronunciation is better, and it can also pay tribute to Wang Jian, the first general of the Qin State, who was the first general of the Qin Dynasty to destroy the six kingdoms. It may be more domineering. Okay, that's it, stop making trouble.

    Sikong Ling has high expectations for his son. My child, the important task of unifying the whole of Africa will be left to you in the future. This land is more magical than the Celestial Empire. There are 54 "great" countries in total. There are constant wars and famines. 1 billion  Black brothers and sisters have a heavier job than destroying the Six Nations.
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